Decide what you’re replacing: use a Tabasco-like vinegar-cayenne option if you need the same tangy heat, or a chili-forward option if you mostly want chili flavor.
Start with the listed ratio (or a smaller amount for baking), then taste after mixing into your base (sauce, dressing, batter).
If your substitute tastes flat or too sweet, add a small splash of vinegar (or lemon) to bring the sharpness closer to Tabasco.
If it’s too spicy, dilute with water, oil, or the dish’s liquid; if it’s not spicy enough, add a pinch of cayenne or chili flakes.
For baking, mix the substitute into wet ingredients first so the heat and vinegar distribute evenly.