Decide what you’re missing: grapefruit’s tang, its grapefruit-like aroma (zest), or its mild bitterness.
Start with the ratio listed for your closest match; use grapefruit juice-to-juice or zest-to-zest behavior.
If the substitute tastes flat, sharpen with a pinch of salt (for sweet drinks) or a tiny splash of citrus.
If it tastes too sharp or too sour, balance with a small amount of sugar/honey; if too mild, add a trace of bitterness.
Taste, then adjust in small increments so the swap doesn’t overpower your recipe’s main flavors.