Match the substitute to your recipe goal: bright savory tang or baking acidity for lift/flavor.
Start with the listed ratio, then taste—especially if your substitute is vinegar-based (you may need a small sweet or water adjustment).
If you need lime-like aroma (salsas, marinades, dressings), add a little lime zest or adjust with a citrus note from the substitute.
For baking, mix the substitute into wet ingredients first so it distributes evenly, then proceed with the recipe.
If your substitute is stronger than lime (vinegar), dilute as noted and re-taste before adding more.