Use a 1:1 ratio: replace taco seasoning with your spice blend measure (same amount by volume/weight).
Taste the dry blend: if it’s flat, add another pinch of garlic powder + onion powder; if it’s too hot, cut chili powder slightly.
If cooking the swap into meat, bloom the spices in the pan for 20–30 seconds before adding liquid (prevents a “raw spice” taste).
If baking (tacos on a sheet pan, stuffed peppers, etc.), mix the blend into your wet seasonings or rub so it disperses evenly.
For extra “store-bought” punch, finish with 1 pinch salt per serving, then adjust at the end of cooking.